In 1978, Eppendorf revolutionized the industry and laboratory workflow with the introduction of the Combitip/Repeater system, and has been the leader in market innovations for the past 35 years. The Eppendorf Combitips advanced have been completely redesigned and optimized to meet all the needs of any modern laboratory. Combitips advanced also function according to the positive displacement principle, thus they always dispense the correct volume independently of the density of the liquid and its flow characteristics (e.g., increased vapor pressure or increased viscosity). Working with radioactive or toxic materials also becomes safer due to the hermetically sealed piston that prevents aerosol contamination.