This nucleic acid test, for use on the cobas liat system, is an automated, rapid multiplex real-time reverse transcription polymerase chain reaction (RT-PCR) test intended for the simultaneous qualitative detection and differentiation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), influenza A virus, influenza B virus, and respiratory syncytial virus (RSV) RNA in 20 minutes from a single nasal and nasopharyngeal sample in just 1 test.