iSED’s micro-flow cell captures the critical kinetics of red blood cells in a highly controlled testing environment. Utilizing a very small sample—100 microliters—the iSED captures the impact of the most critical phase of the early phase in the phenomenon of RBC sedimentation—the so-called rouleaux formation—to produce erthrocyte sedimentation rate (ESR) results that are unaffected by the variables commonly associated with traditional ESR testing, such as mixing of the sample and temperature.