Heat-sealable tubes are premium-quality, sterile packaging products designed to reduce the cost of sterilization processing by including independent indicators imprinted on both the inside and outside of every tube. While external indicators serve as process indicators, the internal indicators monitor the penetration of steam and ethylene-oxide gas on the inside of the package. Not having to add separate indicator strips in the pouches is a cost saving. Made of premium-quality, high-resistance, 2.5-mil plastic and triple-bonded, 75-g medical-grade papers, which guarantees the integrity of the packaging in prevacuum and gravity sterilizations cycles, even with heavy instruments.